Is there a possibility for a new collab or an incoming re-run of previous ones 
Epic Seven continuously expands its connections to different content (collaborations and re-runs). Is there any news or possibility for new collaborations or re-runs on the one's we have with new content?
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New content for re-runs is possible, but shown from over the years they don't add a lot. Like GG added Jacko, Slime added Milim EE and Beni, etc.
There hasn't been any significant content additions like new features, stories, episodes, bosses, games modes yet. I'd be surprised if anything gets added to an Aespa re-run since there's only 4 singers.
It's only recently that they've started adding small new things to collabs like a new hero, EE, or even that new battle game with Green Lilias, so hopefully more detailed content is planned to be added in the future.
Typically there's a new collab every 1+ years, but probably closer to 2. Also Aespa is the latest new collab and only one that hasn't been re-run yet other than Kizuna AI (which I really want..).
When it comes to re-runs, taking into account the last ones we got, most likely (but not certainly) the next one will be either FMA or aespa.
If you're into PVE the best units would probably be GISELLE or Mustang. If you're into PVP the best units are Edward, KARINA, WINTER and, sometimes, Mustang.
Yes, there is, and it is rumored that a rerun is approaching soon. However, at the time of posting this answer, there's no official word on this.